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dc.contributor.authorArcieri, Michael
dc.contributor.authorAgostinelli, Guy
dc.contributor.authorGray, Zach
dc.contributor.authorSpadaro, Amanda N.
dc.contributor.authorLyons, Leslie A.
dc.contributor.authorWebb, Kristen
dc.date.accessioned2018-03-01T14:29:08Z
dc.date.available2018-03-01T14:29:08Z
dc.date.issued2016-02-24
dc.identifier.citationArcieri, M., Agostinelli, G., Grazy, Z., Spadaro, A., Lyons, L.A., and Webb, K. (2016). Establishing a database of Canadian feline mitotypes for forensic use. Forensic Science International: Genetics (22): 169-174. doi: 10.1016/j.fsigen.2016.02.013en_US
dc.identifier.urihttp://hdl.handle.net/10456/45794
dc.description.abstractHair shed by pet animals is often found and collected as evidence from crime scenes. Due to limitations such as small amount and low quality, mitochondrial DNA (mtDNA) is often the only type of DNA that can be used for linking the hair to a potential contributor. mtDNA has lower discriminatory power than nuclear DNA because multiple, unrelated individuals within a population can have the same mtDNA sequence, or mitotype. Therefore, to determine the evidentiary value of a match between crime scene evidence and a suspected contributor, the frequency of the mitotype must be known within the regional population. While mitotype frequencies have been determined for the United States’ cat population, the frequencies are unknown for the Canadian cat population. Given the countries’ close proximity and similar human settlement patterns, these populations may be homogenous, meaning a single, regional database may be used for estimating cat population mitotype frequencies. Here we determined the mitotype frequencies of the Canadian cat population and compared them to the United States’ cat population. The two cat populations are statistically homogenous, however mitotype B6 was found in high frequency in Canada and extremely low frequency in the United States, meaning a single database would not be appropriate for North America. Furthermore, this work calls attention to these local spikes in frequency of otherwise rare mitotypes, instances of which exist around the world and have the potential to misrepresent the evidentiary value of matches compared to a regional database.en_US
dc.language.isoen_USen_US
dc.publisherElsevieren_US
dc.relation.ispartofForensic Science International: Geneticsen_US
dc.relation.isversionofhttp://dx.doi.org/10.1016/j.fsigen.2016.02.013en_US
dc.rightsThis article was selected and published in Forensic Science International: Genetics ©2016 Arcieri, et al. All rights reserved.en_US
dc.subjectmtDNAen_US
dc.subjectmitochondrial DNAen_US
dc.subjectmitotype frequenciesen_US
dc.titleEstablishing a database of Canadian feline mitotypes for forensic useen_US
dc.description.versionPublished articleen_US
dc.contributor.departmentBiologyen_US
dc.citation.volume22en_US
dc.citation.issue1en_US
dc.citation.spage169en_US
dc.citation.epage174en_US
dc.identifier.doi10.1016/j.fsigen.2016.02.013
dc.contributor.avlauthorWebb, Kristen


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