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dc.contributor.authorAngleby, Helen
dc.contributor.authorOskarsson, Mattias
dc.contributor.authorPang, Junfeng
dc.contributor.authorZhang, Ya-ping
dc.contributor.authorLeitmer, Thomas
dc.contributor.authorBraham, Caitlyn
dc.contributor.authorArvestad, Lars
dc.contributor.authorLundeberg, Joakim
dc.contributor.authorWebb, Kristen
dc.contributor.authorSavolainen, Peter
dc.identifier.citationAngleby, H., Oskarsson, M., Pang, J., et al. (2014). Forensic informativity of ~3,000 bp of coding sequence of domestic dog mtDNA. Journal of Forensic Sciences, 59(4): 898-908. doi: 10.1111/1556-4029.12504.en_US
dc.description.abstractThe discriminatory power of the noncoding control region (CR) of domestic dog mitochondrial DNA alone is relatively low. The extent to which the discriminatory power could be increased by analyzing additional highly variable coding regions of the mitochondrial genome (mtGenome) was therefore investigated. Genetic variability across the mtGenome was evaluated by phylogenetic analysis, and the three most variable ~1 kb coding regions identified. We then sampled 100 Swedish dogs to represent breeds in accordance with their frequency in the Swedish population. A previously published dataset of 59 dog mtGenomes collected in the United States was also analyzed. Inclusion of the three coding regions increased the exclusion capacity considerably for the Swedish sample, from 0.920 for the CR alone to 0.964 for all four regions. The number of mtDNA types among all 159 dogs increased from 41 to 72, the four most frequent CR haplotypes being resolved into 22 different haplotypes.en_US
dc.publisherWiley Online Libraryen_US
dc.relation.ispartofJournal of Forensic Sciencesen_US
dc.rightsThis article was selected and published in the Journal of Forensic Sciences ©2014 Angleby, et al. All rights reserved.en_US
dc.subjectforensic scienceen_US
dc.subjectdomestic dogen_US
dc.subjectmitochondrial DNAen_US
dc.subjectcoding regionen_US
dc.subjectcontrol regionen_US
dc.subjectexclusion capacityen_US
dc.titleForensic informativity of ~3,000 bp of coding sequence of domestic dog mtDNA.en_US
dc.title.alternatePaper Criminalisiticsen_US
dc.description.versionPublished articleen_US
dc.contributor.avlauthorWebb, Kristen

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