Short-term supplementation of acute long-chain omega-3 polyunsaturated fatty acids may alter depression status and decrease symptomology among young adults with depression: A preliminary randomized and placebo controlled trial
Persistent URL
Author(s)
Ginty, Annie T.
Conklin, Sarah M.
Date Issued
June 27, 2015
Abstract
The current study examined the psychological effects of acute and low-dose long-chain omega-3 polyunsaturated fatty acids (LCPUFAs) supplementation on young adults with depressive symptoms. Participants (N=23, M age (SD)=20.2 (1.25), 78% female), with a Beck Depression Inventory (BDI) score of greater than 10, were randomly assigned to a placebo (corn oil) or LCPUFAs group (1.4 g of eicosapentaenoic and docosahexaeonic acids) and were instructed to consume the assigned capsules daily for 21-days. BDI was completed prior to supplementation and at day 21. Group differences in depression status on day 21 were analyzed using chi-square tests. After 21-days of supplementation, there was a significant difference in depression status between groups. 67% of the LCPUFAs no longer met criteria for being depressed, while only 20% in the placebo group were no longer depressed. A mixed ANOVA revealed a significant group x time interaction for BDI scores. Post-hoc analyses revealed the LCPFUAs group had a significant reduction in BDI scores over time, while the placebo group's scores did not significantly change. These findings suggest that LCPUFAs may alter depression and depressive symptomology in young adults in a relatively short amount of time.
Journal
Psychiatry Research
Department
Global Health Studies
Neuroscience
Psychology
Citation
Ginty, Annie T. and Sarah M. Conklin. 2015. "Short-term supplementation of acute long-chain omega-3 polyunsaturated fatty acids may alter depression status and decrease symptomology among young adults with depression: A preliminary randomized and placebo controlled trial." Psychiatry Research 229, no. 1: 485-489.
Publisher
Elsevier Ireland Ltd.
Version of Article
Published Article
DOI
10.1016/j.psychres.2015.05.072
ISSN
0165-1781
1872-7123
Rights
Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.
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